Research programme: G-protein coupled receptor modulators - Trevena

Drug Profile

Research programme: G-protein coupled receptor modulators - Trevena

Alternative Names: TRV 0109101

Latest Information Update: 27 Jul 2017

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At a glance

  • Originator Trevena
  • Class Analgesics; Antidepressants; Antiparkinsonians; Small molecules
  • Mechanism of Action G protein-coupled receptor modulators; Opioid delta receptor modulators; Opioid kappa receptor modulators; Opioid mu receptor modulators; Sphingosine 1 phosphate receptor modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Major depressive disorder; Pain; Parkinson's disease; Peripheral nervous system diseases
  • No development reported Cachexia; Inflammation

Most Recent Events

  • 20 Jul 2017 Preclinical trials in Peripheral nervous system diseases in USA
  • 08 Mar 2017 Trevena plans to initiate a first-in-human trial for TRV 250 in Migraine in Q2 2017
  • 18 Mar 2015 Preclinical trials in Migraine in USA (PO) prior to March 2015
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