Research programme: Bruton's tyrosine kinase inhibitors - Pharmacyclics

Drug Profile

Research programme: Bruton's tyrosine kinase inhibitors - Pharmacyclics

Alternative Names: PCI-45261; PCI-45292

Latest Information Update: 28 May 2015

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At a glance

  • Originator Pharmacyclics
  • Class Small molecules
  • Mechanism of Action Agammaglobulinaemia tyrosine kinase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Autoimmune disorders; Hypersensitivity; Rheumatoid arthritis

Most Recent Events

  • 26 May 2015 Pharmacyclics has been acquired by AbbVie
  • 31 Mar 2014 A lead candidate Btk inhibitor has entered clinical development for Rheumatoid arthritis in the USA
  • 31 Jan 2014 Pharmacyclics files an IND application with the FDA in USA for Inflammation and Autoimmune disorders
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