Drug Profile


Alternative Names: RO-5025181; RO5025181-000; SYN-120

Latest Information Update: 02 Mar 2017

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At a glance

  • Originator Roche
  • Developer Acorda Therapeutics; Biotie Therapies Corp.
  • Class Antiparkinsonians; Nootropics; Small molecules
  • Mechanism of Action Serotonin 2A receptor antagonists; Serotonin 6 receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes
  • Available For Licensing Yes - Alzheimer's disease; Cognition disorders

Highest Development Phases

  • Phase II Parkinson's disease
  • No development reported Cognition disorders

Most Recent Events

  • 01 Mar 2017 Phase-II development for Parkinson’s disease-related dementia is ongoing in USA (PO)
  • 01 Mar 2017 No recent reports on development identified - Phase-I for Cognition disorders in USA (PO)
  • 25 Jan 2017 Chemical structure information added
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