SD 101 - Dynavax

Drug Profile

SD 101 - Dynavax

Alternative Names: SD-101 - Dynavax

Latest Information Update: 13 Sep 2017

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At a glance

  • Originator Dynavax Technologies
  • Developer Dynavax Technologies; Merck & Co; National Cancer Institute (USA); Stanford University School of Medicine
  • Class Oligodeoxyribonucleotides
  • Mechanism of Action Immunostimulants; Toll-like receptor 9 agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Phase I/II B cell lymphoma; Follicular lymphoma; Malignant melanoma
  • Phase I Haematological malignancies; Lymphoma
  • No development reported Hepatitis C

Most Recent Events

  • 02 Jun 2017 Updated efficacy, adverse events and pharmacodynamics data from a phase Ib/II trial in Malignant melanoma presented at the 53rd Annual Meeting of American Society of Clinical Oncology (ASCO-2017)
  • 01 Apr 2017 Dynavax Technologies Corporation completes a phase I/II trial in B-cell lymphoma (First-line therapy) in USA (Intratumoural) (NCT02266147)
  • 06 Mar 2017 Updated interim adverse events, pharmacodynamics and efficacy data from a phase Ib/II trial in Malignant melanoma released by Dynavax
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