Sotagliflozin

Drug Profile

Sotagliflozin

Alternative Names: [14C]-LX4211; LP-802034; LX-4211; SAR 439954

Latest Information Update: 18 Sep 2017

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At a glance

  • Originator Lexicon Pharmaceuticals
  • Developer Lexicon Pharmaceuticals; Sanofi
  • Class Alcohols; Antihyperglycaemics; Glycosides; Pyrans; Small molecules; Sulfhydryl compounds
  • Mechanism of Action Sodium-glucose transporter 1 inhibitors; Sodium-glucose transporter 2 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Type 1 diabetes mellitus; Type 2 diabetes mellitus

Most Recent Events

  • 13 Sep 2017 Efficacy data from the phase III inTandem3 trial in Type-1 diabetes mellitus, which met its primary endpoint, released by Lexicon Pharmaceuticals
  • 11 Sep 2017 Pooled analysis of efficacy data from the phase III TANDEM 1 and TANDEM 1 trials in Type 2 diabetes mellitus released by Lexicon Pharmaceuticals
  • 22 Aug 2017 Sanofi completes a phase I trial in bioequivalence trial for Type 2 diabetes mellitus in USA (NCT03211195)
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