AEVI 002

Drug Profile

AEVI 002

Alternative Names: Anti-CD258 monoclonal antibody; Anti-LIGHT monoclonal antibody; MDGN-002; SAR 252067

Latest Information Update: 02 Aug 2017

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At a glance

  • Originator Kyowa Hakko Kirin; La Jolla Institute for Allergy & Immunology
  • Developer Aevi Genomic Medicine; Kyowa Hakko Kirin; Sanofi; The Childrens Hospital of Philadelphia
  • Class Monoclonal antibodies
  • Mechanism of Action Immunomodulators; Tumour necrosis factor ligand superfamily member 14 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Crohn's disease
  • Discontinued Ulcerative colitis

Most Recent Events

  • 14 Jul 2017 Phase-I clinical trials in Crohn's disease (In adults, Treatment-experienced) in USA (SC) (NCT03169894)
  • 02 Jun 2017 Aevi Genomic Medicine plans a phase I trial for Crohn's Disease in USA (SC) (NCT03169894)
  • 15 Dec 2016 Medgenics is now called Aevi Genomic Medicine
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