Drug Profile
NMS 1116354
Alternative Names: NMS-1116354; NMS-354; PHA-767491Latest Information Update: 05 Feb 2013
Price :
$50
*
At a glance
- Originator Nerviano Medical Sciences
- Class Antineoplastics; Piperidones; Pyrroles; Small molecules
- Mechanism of Action CDC7 protein kinase inhibitors; DNA synthesis inhibitors
-
Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
Highest Development Phases
- Discontinued Solid tumours
Most Recent Events
- 05 Feb 2013 Discontinued - Phase-I for Solid tumours in France (PO)
- 05 Feb 2013 Discontinued - Phase-I for Solid tumours in USA (PO)
- 16 Nov 2010 Efficacy, adverse events and pharmacokinetics data from a phase I trial in Solid tumours presented at the 22nd EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics (EORTC-NCI-AACR-2010)