THR 18

Drug Profile

THR 18

Alternative Names: Plasminogen activator inhibitor-1-derived 18-mer peptide; THR-18

Latest Information Update: 10 Dec 2015

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At a glance

  • Originator Hadassah Medical Organization
  • Developer D-Pharm; Thrombotech
  • Class Antithrombotics; Neuroprotectants; Peptides
  • Mechanism of Action Plasminogen activator inhibitor-1 modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Stroke
  • Phase I Myocardial infarction; Pulmonary embolism

Most Recent Events

  • 15 Dec 2016 Biomarkers information updated
  • 16 Nov 2015 Phase-II clinical trials in Stroke (Combination therapy) in Moldova (IV) (NCT02572336 )
  • 03 Oct 2015 D-Pharm plans a phase II trial for Stroke (Combination therapy) in Moldova (IV) (NCT02572336)
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