AUS 131

Drug Profile

AUS 131

Alternative Names: AUS-131; S-equol

Latest Information Update: 04 Nov 2017

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At a glance

  • Originator Ausio Pharmaceuticals
  • Developer Ausio Pharmaceuticals; University of Kansas Medical Center; University of Texas Health Science Center at San Antonio
  • Class Isoflavones; Small molecules
  • Mechanism of Action Estrogen receptor beta agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No
  • Available For Licensing Yes

Highest Development Phases

  • Phase II Benign prostatic hyperplasia; Vasomotor symptoms
  • Phase I/II Alzheimer's disease
  • Phase 0 Breast cancer
  • No development reported Osteoporosis

Most Recent Events

  • 04 Nov 2017 No recent reports of development identified for phase-I development in Osteoporosis(In volunteers) in USA (PO, Capsule)
  • 05 May 2017 Phase-I/II clinical trials in Alzheimer's disease in USA (PO) (NCT03101085)
  • 07 Apr 2017 University of Kansas Medical Center and Ausio Pharmaceuticals plan the phase I/II SEAD2 I trial for Alzheimer's disease in USA (NCT03101085)
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