IGF-methotrexate conjugate - IGF Oncology

Drug Profile

IGF-methotrexate conjugate - IGF Oncology

Alternative Names: 765-IGF-MTX; IGF-methotrexate conjugate; IGF/MTX

Latest Information Update: 08 May 2017

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At a glance

  • Originator IGF Oncology
  • Developer IGF Oncology; University of Chicago
  • Class Antineoplastics; Benzamides; Drug conjugates; Glutamates; Growth factors; Peptides; Pterins; Small molecules; Somatomedins
  • Mechanism of Action Immunosuppressants; Tetrahydrofolate dehydrogenase inhibitors; Thymidylate synthase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Phase I Solid tumours

Most Recent Events

  • 08 Jun 2017 IGF Oncology plans a phase I/II trial for Myelodysplastic syndrome and Myeloid leukaemia (Late-stage disease, Second-line therapy or greater) in USA (NCT03175978)
  • 15 Dec 2016 Biomarkers information updated
  • 30 Sep 2016 University of Illinois at Chicago and IGF Oncology completes a phase I trial in Solid tumours (Second-line therapy or greater, Late-stage disease) in USA (NCT02045368)
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