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Suvemcitug - Simcere Pharmaceutical Group

Drug Profile

Suvemcitug - Simcere Pharmaceutical Group

Alternative Names: Anti-VEGF monoclonal antibody - Pyxis Oncology; APX-003; BD-0801; EP-10030; Sevacizumab - Pyxis Oncology; SIM-BD-0801

Latest Information Update: 25 Mar 2024

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At a glance

  • Originator Epitomics
  • Developer Jiangsu T-mab BioPharma; Simcere Pharmaceutical Group
  • Class Antineoplastics; Eye disorder therapies; Immunotherapies; Monoclonal antibodies
  • Mechanism of Action Antibody-dependent cell cytotoxicity; T lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Fallopian tube cancer; Ovarian cancer; Peritoneal cancer
  • Phase II Colorectal cancer; Solid tumours
  • Discontinued Wet age-related macular degeneration

Most Recent Events

  • 13 Mar 2024 Jiangsu Simcere Pharmaceutical terminated a phase II trial in Solid tumours (Combination therapy, Late-stage disease, Second-line therapy or greater) in China (SC), due to the sponsor's research and development strategy adjustment (NCT05148195)
  • 01 Nov 2023 Phase-III clinical trials in Fallopian tube cancer in China (IV) prior to November 2023 (Simcere Pharmaceutical Group pipeline, November 2023)
  • 01 Nov 2023 Phase-III clinical trials in Ovarian cancer in China (IV) prior to November 2023 (Simcere Pharmaceutical Group pipeline, November 2023)
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