MEDI 3617

Drug Profile

MEDI 3617

Alternative Names: ANG-2 mAb; Anti-ANG-2 mAb; MEDI3617

Latest Information Update: 14 Dec 2015

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At a glance

  • Originator MedImmune
  • Developer Dana-Farber Cancer Institute; MedImmune
  • Class Antineoplastics; Monoclonal antibodies
  • Mechanism of Action Angiopoietin-2 inhibitors; TIE 2 receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Malignant melanoma; Solid tumours
  • Preclinical Rheumatoid arthritis

Most Recent Events

  • 15 Dec 2016 Biomarkers information updated
  • 08 Oct 2015 Phase-I development for Malignant melanoma (Inoperable/Unresectable, Combination therapy, Metastatic disease) is ongoing in USA (NCT02141542)
  • 04 Jun 2014 Interim adverse events and efficacy data from a phase I trial in Solid tumours presented at the 50th Annual Meeting of the American Society of Clinical Oncology (ASCO-2014)
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