Research programme: cancer therapeutics - OncoMed

Drug Profile

Research programme: cancer therapeutics - OncoMed

Alternative Names: Anti-cancer stem cell monoclonal antibodies - OncoMed; Anti-CSC monoclonal antibodies - OncoMed; Anti-tumour-initiating cell monoclonal antibodies - OncoMed; GITRL-Fc; I/O#2; IO#2; IO#3; OMP-336B11

Latest Information Update: 25 Jan 2017

Price : $50

At a glance

  • Originator OncoMed Pharmaceuticals
  • Class Bispecific antibodies; Monoclonal antibodies
  • Mechanism of Action DLL4 protein inhibitors; Notch-1 receptor antagonists; Notch-2 receptor antagonists; Notch-3 receptor antagonists; RSPO3 protein inhibitors; Stem cell modulators; TNFRSF18 protein modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • On Fast track

    Fast track status is assigned by the US FDA so therapies with the potential to address unmet needs can move faster through development.

  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Cancer

Most Recent Events

  • 05 Jan 2017 OncoMed intends to file an IND application for OMP 336B11 for Cancer in the first half of 2017
  • 19 Aug 2016 Preclinical development is ongoing in USA in Cancer
  • 16 Jul 2016 No recent reports of development identified for preclinical development in Cancer in USA (Parenteral)
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