Entolimod

Drug Profile

Entolimod

Alternative Names: CBLB 502

Latest Information Update: 25 Apr 2017

$50 / €47 *
* $ price applies to USA, Canada and Latin America. € price applies to the rest of the world. Final gross prices may vary according to local VAT.

At a glance

  • Originator Cleveland BioLabs
  • Class Anti-ischaemics; Antidotes; Antineoplastics; Chemoprotectants; Peptides; Radioprotectives
  • Mechanism of Action Apoptosis inhibitors; NF-kappa B modulators; Toll-like receptor 5 agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Acute radiation syndrome
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Colorectal cancer
  • Phase I Acute radiation syndrome; Cancer
  • Preclinical Radiation injuries
  • No development reported Reperfusion injury

Most Recent Events

  • 17 Apr 2017 EMA accepts Paediatric Investigation Plan (PIP) filed by Cleveland bioLabs as a medical radiation countermeasure
  • 17 Apr 2017 US FDA provides consent to Cleveland BioLabs to conduct in vivo biocomparability study of two formulations of entolimod in non-human primates
  • 27 Feb 2017 Baylor College of Medicine in collaboration with National Institutes of Health plans a phase I trial for Substance related disorders in USA (NCT03063736)
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