Entolimod

Drug Profile

Entolimod

Alternative Names: CBLB 502

Latest Information Update: 20 Apr 2017

Price : $50

At a glance

  • Originator Cleveland BioLabs
  • Class Anti-ischaemics; Antidotes; Chemoprotectants; Peptides
  • Mechanism of Action Apoptosis inhibitors; NF-kappa B modulators; Toll-like receptor 5 agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Acute radiation syndrome
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Cancer
  • Phase I Acute radiation syndrome
  • Preclinical Radiation injuries
  • No development reported Reperfusion injury

Most Recent Events

  • 17 Apr 2017 US FDA provides consent to Cleveland BioLabs to conduct in vivo biocomparability study of two formulations of entolimod in non-human primates
  • 27 Feb 2017 Baylor College of Medicine in collaboration with National Institutes of Health plans a phase I trial for Substance related disorders in USA (NCT03063736)
  • 14 Nov 2016 Cleveland BioLabs completes enrollment in the phase II trial for Cancer (First-line therapy, Neoadjuvant therapy) in Russia (NCT02715882; 9207054)
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