Drug Profile


Alternative Names: AMG 203; Amg203; MT-203

Latest Information Update: 10 Sep 2017

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At a glance

  • Originator Micromet Inc
  • Developer Takeda Pharmaceuticals International GmbH
  • Class Anti-inflammatories; Antipsoriatics; Antirheumatics; Monoclonal antibodies
  • Mechanism of Action Granulocyte macrophage colony stimulating factor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Rheumatoid arthritis
  • Discontinued Plaque psoriasis

Most Recent Events

  • 10 May 2017 Discontinued - Phase-II for Plaque psoriasis (In the elderly, In adults) in Latvia, Poland, Germany, Denmark, and Canada (SC) because a phase II trial did not meet its primary endpoint (Takeda FY2016 Q4 results, May 2017)
  • 15 Dec 2016 Biomarkers information updated
  • 01 Dec 2016 Takeda completes the TELLUS trial in Rheumatoid arthritis (Combination therapy, In adults, In elderly) in United Kingdom, Czech Republic, Estonia, Spain (EudraCT2014-002945-23)
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