Bryostatin 1 analogues - Aphios

Drug Profile

Bryostatin 1 analogues - Aphios

Alternative Names: APH-0703; APH-1104; Bryosomes; Bryostatin 1-containing phospholipid nanosomes (Bryosomes™) - Aphios; Nanoencapsulated APH 0703

Latest Information Update: 24 Sep 2015

Price : $50

At a glance

  • Originator Aphios Corporation
  • Developer Aphios Corporation; Louisiana State University
  • Class Antineoplastics; Macrocyclic compounds
  • Mechanism of Action Protein kinase C stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No
  • Available For Licensing Yes

Highest Development Phases

  • Preclinical Alzheimer's disease; Cognition disorders
  • Discontinued Oesophageal cancer

Most Recent Events

  • 20 Oct 2014 Discontinued - Preclinical for Oesophageal cancer (New delivery system) in USA (Parenteral)
  • 20 Oct 2014 Aphios is investigating oral bryostatin 1 analogue, APH 1104, for the treatment of Alzheimer's disease and Cognition disorders in USA
  • 20 Oct 2014 Bryostatin 1 analogues - Aphios is available for licensing -
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