ADX 71149

Drug Profile

ADX 71149

Alternative Names: ADX-71149; JNJ-40411813; JNJ-mGluR2-PAM

Latest Information Update: 10 Sep 2017

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At a glance

  • Originator Addex Pharmaceuticals
  • Developer Addex Therapeutics; Janssen Pharmaceuticals
  • Class Antidepressants; Antipsychotics; Anxiolytics; Small molecules
  • Mechanism of Action Metabotropic glutamate receptor 2 modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Epilepsy
  • Discontinued Major depressive disorder; Psychiatric disorders; Schizophrenia

Most Recent Events

  • 27 Feb 2017 Addex Therapeutics and Janssen Pharmaceuticals plan a phase IIa proof of concept trial for Epilepsy
  • 06 Dec 2016 Discontinued - Phase-I for Psychiatric disorders (In volunteers) in USA (PO) (Addex Therapeutics pipeline, December 2016)
  • 06 Dec 2016 Discontinued - Phase-II for Schizophrenia (Adjunctive treatment) in Bulgaria, Spain, Romania, Germany, Belgium, Austria (PO) (Addex Therapeutics pipeline, December 2016)
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