PBI 4050

Drug Profile

PBI 4050

Alternative Names: PBI-4050

Latest Information Update: 27 Dec 2016

Price : $50

At a glance

  • Originator ProMetic Life Sciences
  • Developer ProMetic Life Sciences; Vanderbilt University
  • Class Anti-inflammatories; Antifibrotics; Small molecules
  • Mechanism of Action Cell differentiation modulators; Colony stimulating factor stimulants; Cytokine modulators; Erythropoiesis stimulants; Extracellular matrix protein inhibitors; Extracellular matrix protein modulators; Immunomodulators; Inflammation mediator inhibitors; Inflammation mediator modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Idiopathic pulmonary fibrosis
  • On Fast track

    Fast track status is assigned by the US FDA so therapies with the potential to address unmet needs can move faster through development.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Diabetic nephropathies; Idiopathic pulmonary fibrosis; Inborn genetic disorders; Metabolic syndrome
  • Preclinical Cystic fibrosis; Pulmonary arterial hypertension; Renal fibrosis; Scleroderma
  • No development reported Anaemia; Haematological disorders; Neutropenia

Most Recent Events

  • 21 Nov 2016 ProMetic initiates enrolment in a phase II trial for Idiopathic pulmonary fibrosis in Canada before November 2016
  • 16 Nov 2016 ProMetic Life Sciences receives clearance from Health Canada for a phase II trial for Metabolic syndrome and Type-2 diabetes mellitus
  • 16 Nov 2016 ProMetic Life Sciences plans a phase II trial in Metabolic syndrome (in patients with Type-2 diabetes mellitus) in Canada
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