Drug Profile


Alternative Names: LCQ 908; LCQ908-NXA; LCQ908A; Pradigastat sodium

Latest Information Update: 10 Sep 2017

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At a glance

  • Originator Novartis
  • Class Aminopyridines; Antihyperglycaemics; Antihyperlipidaemics; Cyclohexanecarboxylic acids; Obesity therapies; Small molecules
  • Mechanism of Action Diacylglycerol O acyltransferase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Hyperlipoproteinaemia type I
  • No development reported Coronary artery disease; Hyperlipoproteinaemia type V; Hyperlipoproteinaemias; Non-alcoholic fatty liver disease; Obesity; Type 2 diabetes mellitus
  • Discontinued Hepatitis C

Most Recent Events

  • 15 Dec 2016 Biomarkers information updated
  • 11 Sep 2015 No recent reports on development identified - Phase-I/II for Hyperlipoproteinaemia type V in Canada (PO)
  • 12 May 2015 Phase-III is still ongoing for Hyperlipoproteinaemia type I in the United Kingdom, Spain, Canada, Netherlands and Germany
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