Drug Profile


Alternative Names: Amphinex; PC-A11; PC-A22; TPCS-2A

Latest Information Update: 22 Jul 2017

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At a glance

  • Originator PCI Biotech
  • Developer Norwegian Radium Hospital; PCI Biotech; University Hospital Zurich
  • Class Antineoplastics; Benzenesulfonates; Porphyrins; Small molecules
  • Mechanism of Action Photosensitisers
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No
  • Available For Licensing Yes - Cancer

Highest Development Phases

  • Phase I/II Cholangiocarcinoma
  • Preclinical Malignant melanoma
  • Discontinued Bladder cancer; Head and neck cancer

Most Recent Events

  • 19 Apr 2017 Interim adverse events and efficacy data from a phase-I/II trial in Cholangiocarcinoma presented at the International Liver Congress (ILC-2017)
  • 06 Sep 2016 Interim adverse events and efficacy data from a phase I/II trial in Cholangiocarcinoma released by PCI Biotech
  • 01 Sep 2016 PCI Biotech initiates enrolment in the phase I trial in healthy volunteers in the United Kingdom (NCT02947854)
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