Research programme: monoclonal antibody therapeutics - argenx/Bird Rock Bio

Drug Profile

Research programme: monoclonal antibody therapeutics - argenx/Bird Rock Bio

Alternative Names: Anti-interleukin 22 monoclonal antibody; Anti-Nav1.7 monoclonal antibody; ARGX-112; LP 0145; Monoclonal antibodies targeting GPCR receptors - Bird Rock Bio

Latest Information Update: 02 Mar 2017

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At a glance

  • Originator arGEN-X
  • Developer argenx; Bird Rock Bio
  • Class Monoclonal antibodies
  • Mechanism of Action G protein-coupled receptor modulators; Interleukin 22 receptor antagonists; Interleukin 6 inhibitors; Nav1.7-voltage-gated-sodium-channel-inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Preclinical Autoimmune disorders; Cancer; Inflammation; Ovarian cancer; Pain; Renal cancer; Skin disorders

Most Recent Events

  • 21 May 2015 arGEN-X and LEO Pharma agree to collaborate on monoclonal antibody therapeutics, including ARGX 112, for inflammatory Skin disorders
  • 18 Feb 2015 arGEN-X in-licenses GS Xceed™ System technology from Lonza )
  • 27 Mar 2014 RuiYi secures loan ($US15 million in Series B financing) from existing investors to finance development of RYI 008 and the discovery and development of therapeutic mAbs targeting GPCR receptors (including RYI 018) for Autoimmune diseases and Cancer
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