Research programme: naloxegol/opioid analgesic combination - AstraZeneca/Nektar

Drug Profile

Research programme: naloxegol/opioid analgesic combination - AstraZeneca/Nektar

Alternative Names: Naloxegol/opioid; NKTR-118/opioid - Nektar Therapeutics/AstraZeneca; NKTR-119

Latest Information Update: 04 Nov 2017

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At a glance

  • Originator Nektar Therapeutics
  • Developer AstraZeneca; Nektar Therapeutics
  • Class Opioid analgesics
  • Mechanism of Action Opioid mu receptor agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • No development reported Pain

Most Recent Events

  • 04 Nov 2017 No recent reports of development identified for preclinical development in Pain in USA (PO)
  • 11 Jun 2014 The Anesthetic and Analgesic Drug Products Advisory Committee of the US FDA schedules a meeting to assess potential cardiovascular risk associated with peripherally-acting opioid receptor antagonists, including naloxegol
  • 14 Jan 2014 Preclinical development of NKTR 119 is ongoing
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