Drug Profile


Alternative Names: AIC-001; AIC-090027; AIC-246; BAY-73-6327; MK-8228

Latest Information Update: 10 Sep 2017

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At a glance

  • Originator Bayer
  • Developer Merck & Co
  • Class Acetates; Antivirals; Fluorobenzenes; Phenyl ethers; Piperazines; Quinazolines; Small molecules
  • Mechanism of Action Cytomegalovirus replication inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Cytomegalovirus infections
  • New Molecular Entity Yes

Highest Development Phases

  • Preregistration Cytomegalovirus infections

Most Recent Events

  • 12 May 2017 Efficacy data from a phase III trial in Cytomegalovirus infections (Prevention) presented at the 27th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID-2017)
  • 03 May 2017 Preregistration for Cytomegalovirus infections (Prevention) in European Union before May 2017 (IV, PO)
  • 28 Feb 2017 Merck has patent protection for Letermovir in USA (Merck Annual report 2016)
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