AGT 181

Drug Profile

AGT 181

Alternative Names: AGT-181; cTfRMAb-IDUA murine fusion protein; HIRMAb-IDUA; IgG-alpha-L-iduronidase fusion protein; IgG-IDUA fusion protein; Recombinant human insulin receptor monoclonal antibody-fused alpha-L-iduronidase

Latest Information Update: 02 Apr 2016

Price : $50

At a glance

  • Originator ArmaGen Technologies
  • Class Immunoglobulin fusion proteins; Monoclonal antibodies
  • Mechanism of Action Iduronidase replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Mucopolysaccharidosis I
  • On Fast track

    Fast track status is assigned by the US FDA so therapies with the potential to address unmet needs can move faster through development.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Mucopolysaccharidosis I

Most Recent Events

  • 01 Mar 2016 Phase-II clinical trials in Mucopolysaccharidosis I (In children) in Brazil (IV)
  • 01 Mar 2016 ArmaGen completes a phase I trial in Mucopolysaccharidosis I (In adults) in Brazil (IV) before March 2016
  • 05 Nov 2015 AGT 181 receives rare paediatric disease status for Mucopolysaccharidosis I in USA
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