AGT 181

Drug Profile

AGT 181

Alternative Names: AGT-181; cTfRMAb-IDUA murine fusion protein; HIRMAb-IDUA; IgG-alpha-L-iduronidase fusion protein; IgG-IDUA fusion protein; Recombinant human insulin receptor monoclonal antibody-fused alpha-L-iduronidase

Latest Information Update: 08 Mar 2017

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At a glance

  • Originator ArmaGen Technologies
  • Class Immunoglobulin fusion proteins; Monoclonal antibodies
  • Mechanism of Action Iduronidase replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Mucopolysaccharidosis I
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Mucopolysaccharidosis I

Most Recent Events

  • 16 Feb 2017 Adverse events and efficacy data from a phase II trial in Mucopolysaccharidosis I released by ArmaGen
  • 01 Oct 2016 ArmaGen initiates enrolment in a phase I/II trial for Mucopolysaccharidosis I in Brazil (NCT03071341)
  • 01 Mar 2016 Phase-II clinical trials in Mucopolysaccharidosis I (In children) in Brazil (IV)
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