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VB 201

Drug Profile

VB 201

Alternative Names: CI-201; VB-201

Latest Information Update: 14 Feb 2023

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At a glance

  • Originator VBL Therapeutics
  • Class Anti-inflammatories; Antifibrotics; Hepatoprotectants; Phospholipids; Small molecules
  • Mechanism of Action CD14 antigen inhibitors; Cell movement inhibitors; Interleukin 12 subunit p40 inhibitors; Phospholipid modulators; Toll like receptor 2 antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase II Atherosclerosis; COVID 2019 infections
  • No development reported Hepatic fibrosis; Inflammatory bowel diseases; Multiple sclerosis; Non-alcoholic fatty liver disease; Renal fibrosis; Rheumatoid arthritis
  • Discontinued Plaque psoriasis; Ulcerative colitis

Most Recent Events

  • 25 Oct 2022 VBL Therapeutics completes a phase II trial for COVID-2019 infections in Israel (PO) (NCT04733833)
  • 28 Sep 2022 No recent reports of development identified for preclinical development in Renal-fibrosis in Israel (PO, Capsule)
  • 25 Jun 2021 University of California plans a phase I/II VITAL HIV trial in Inflammation (in treated HIV) in USA (PO, Tablet) in July 2022 (NCT04939311)
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