Drug Profile


Alternative Names: AMG-212; BAY-2010112; MT-112; PSMA BiTE Antibody

Latest Information Update: 28 Apr 2016

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At a glance

  • Originator Micromet Inc
  • Developer Amgen; Bayer HealthCare Pharmaceuticals
  • Class Antineoplastics; Bispecific antibodies; Immunoglobulin Fv fragments; Monoclonal antibodies
  • Mechanism of Action Immunostimulants; T lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Prostate cancer

Most Recent Events

  • 04 Apr 2016 Pasotuxizumab is still in phase I trials for Prostate cancer (Hormone refractory, Late-stage disease) in Austria and Germany (SC)
  • 07 Oct 2015 Phase-I clinical trials in Prostate cancer (Hormone refractory, Late-stage disease) in Austria and Germany (IV)
  • 24 Apr 2012 Bayer and Amgen plan a phase I trial for Prostate cancer
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