Research programme: cancer therapeutics - PHusis Therapeutics

Drug Profile

Research programme: cancer therapeutics - PHusis Therapeutics

Alternative Names: PHT-427; PHT-7.3

Latest Information Update: 06 Jun 2017

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At a glance

  • Originator PHusis Therapeutics
  • Class Antineoplastics; Small molecules
  • Mechanism of Action 3-phosphoinositide dependent-protein-kinase-inhibitors; KRAS protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Malignant melanoma; Solid tumours

Most Recent Events

  • 02 Jun 2017 PHT 427 is still in pre-clinical trials for Solid tumours in USA (PHusis Therapeutics website, June 2017)
  • 02 Jun 2017 PHusis plans phase I trials for PHT 427 and PHT 7.3 (PHusis Therapeutics website, June 2017)
  • 01 Apr 2017 Pharmacodynamics data from preclinical trials in Solid tumours presented at the 108th Annual Meeting of the American Association for Cancer Research (AACR-2017)
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