Research programme: antibody-drug conjugates - ImmunoGen

Drug Profile

Research programme: antibody-drug conjugates - ImmunoGen

Alternative Names: Anti-ADAM9 antibody-drug conjugates; Anti-c-Met-DGN 549; Anti-c-Met-DM4; anti-CD123 ADC - Immunogen; Anti-CD33-3m; Anti-CD56-3m; Anti-cMet antibody-drug conjugate; Anti-EGFR-3m; Anti-FRα-3m; CD19-targeting antibody-drug conjugate; huB4-DGN462; hucMet-DM4; hucMet27-DGN 549; IGN P1; IGNs-ADCs; M-DGN549; M9346A NL DM

Latest Information Update: 28 Apr 2017

Price : $50

At a glance

  • Originator ImmunoGen
  • Class Antineoplastics; Drug conjugates; Immunoconjugates; Maytansinoids; Monoclonal antibodies; Small molecules
  • Mechanism of Action ADAM9 protein modulators; Alkylating agents; CD19 antigen inhibitors; CD33 antigen inhibitors; CD56 antigen inhibitors; DNA cross linking agents; Epidermal growth factor receptor antagonists; Folate receptor 1 antagonists; Proto oncogene protein c met inhibitors; Tubulin inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Solid tumours

Most Recent Events

  • 01 Apr 2017 Pharmacodynamics data from preclinical trials in Solid tumours presented at the 108th Annual Meeting of the American Association for Cancer Research (AACR-2017)
  • 01 Apr 2017 Pharmacodynamics data from a preclinical trial in Solid tumours presented at the 108th Annual Meeting of the American Association for Cancer Research (AACR-2017) (Parenteral)
  • 15 Nov 2016 Preclinical data of M DGN 549 presented at the 28th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics(EORTC-NCI-AACR-2016)
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