Poziotinib

Drug Profile

Poziotinib

Alternative Names: HM-78136B; NOV-120101

Latest Information Update: 11 Oct 2017

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At a glance

  • Originator Hanmi Pharmaceutical
  • Developer Chonnam National University Hospital; Chungnam National University; Hanmi Pharmaceutical; Konkuk University Medical Center; Korean Association for the Study of Targeted Therapys; Kosin University Gospel Hospital; Kyungpook National University Medical School; Spectrum Pharmaceuticals; University of Texas M. D. Anderson Cancer Center; Yonsei University Health System
  • Class Anilinouracils; Antineoplastics; Piperidines; Quinazolines; Small molecules
  • Mechanism of Action Epidermal growth factor receptor antagonists; ERBB 2 receptor antagonists; ERBB 4 receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Breast cancer; Gastric cancer; Head and neck cancer; Lung cancer; Non-small cell lung cancer
  • Clinical Phase Unknown Colorectal cancer

Most Recent Events

  • 28 Sep 2017 Initial efficacy and adverse events data from a phase II trial in Non-small cell lung cancer released by Spectrum Pharmaceuticals
  • 28 Sep 2017 Pharmacodynamics data from preclinical trials in Non-small cell lung cancer released by Spectrum Pharmaceuticals
  • 08 Sep 2017 Efficacy and adverse events data from a phase II trial in Breast cancer presented at the 42nd European Society for Medical Oncology Congress (ESMO-2017)
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