Amiloride/spironolactone - Hemodynamic Therapeutics

Drug Profile

Amiloride/spironolactone - Hemodynamic Therapeutics

Alternative Names: amiloride hydrochloride/spironolactone; HTI-101; spironolactone/amiloride; spironolactone/amiloride-hydrochloride

Latest Information Update: 14 Sep 2017

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At a glance

  • Originator University of Alabama
  • Class Antihormones; Antihypertensives; Lactones; Pregnenes; Pyrazines; Small molecules
  • Mechanism of Action Aldosterone antagonists; Potassium-sparing diuretics; Sodium channel antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • No development reported Resistant hypertension

Most Recent Events

  • 14 Sep 2017 Chemical structure information added
  • 03 Aug 2015 No recent reports on development identified - Phase-II for Resistant hypertension in USA (PO)
  • 14 Dec 2009 HTI 101 is available for collaboration for development and commercialisation (
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