OTX 008

Drug Profile

OTX 008

Alternative Names: OTX-008; PTX-008

Latest Information Update: 20 Dec 2014

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At a glance

  • Originator PepTx
  • Developer OncoEthix
  • Class Antineoplastics; Calixarenes; Small molecules
  • Mechanism of Action Galectin-1-inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Solid tumours

Most Recent Events

  • 18 Dec 2014 OncoEthix has been acquired by Merck & Co
  • 22 Oct 2013 In vitro pharmacodynamics data in Cancer presented at the 25th AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics (AACR-NCI-EORTC-2013)
  • 01 Feb 2012 Phase-I clinical trials in Solid tumours (second-line therapy or greater) in Belgium (SC)
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