Research programme: cancer metabolism therapeutics - Agios/Celgene

Drug Profile

Research programme: cancer metabolism therapeutics - Agios/Celgene

Alternative Names: AGI-14100; Glutaminase - Agios/Celgene; isocitrate dehydrogenase inhibitors - Agios/Celgene

Latest Information Update: 16 Jul 2016

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At a glance

  • Originator Agios Pharmaceuticals
  • Class Small molecules
  • Mechanism of Action Glutamine inhibitors; Isocitrate dehydrogenase 1 inhibitors; Isocitrate dehydrogenase 2 inhibitors; Phosphofructokinase modulators; Pyruvate kinase modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Acute myeloid leukaemia; Myelodysplastic syndromes
  • Research Cancer
  • No development reported Brain cancer

Most Recent Events

  • 16 Jul 2016 No recent reports of development identified for preclinical development in Brain-cancer in USA (PO)
  • 17 May 2016 Agios Pharmaceuticals and Celgene Corporation agree to co-develop metaboli immuno oncology therapeutics
  • 11 Dec 2013 Agios and Celgene extend their collaboration until 2015
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