Research programme: proteostasis regulators - Proteostasis Therapeutics

Drug Profile

Research programme: proteostasis regulators - Proteostasis Therapeutics

Alternative Names: PTI 808; PTI NC 733; PTI-130; PTI-801 - Proteostasis Therapeutics; PTI-C1811; PTI-P271

Latest Information Update: 21 Oct 2016

Price : $50

At a glance

  • Originator Proteostasis Therapeutics
  • Developer Biogen; Cystic Fibrosis Foundation Therapeutics; Harvard Medical School; Proteostasis Therapeutics
  • Class Small molecules
  • Mechanism of Action Alpha-synuclein inhibitors; Cystic fibrosis transmembrane conductance regulator stimulants; Protein folding modulators; Protein modulators; USP14 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Chronic obstructive pulmonary disease; Cystic fibrosis; Neurodegenerative disorders
  • Research Inflammation; Metabolic disorders; Parkinson's disease

Most Recent Events

  • 30 Mar 2017 Proteostasis Therapeutics plans to file an IND application with the US FDA for Cystic fibrosis
  • 30 Mar 2017 Proteostasis Therapeutics plans a phase I trial for Cystic fibrosis
  • 11 Aug 2016 Proteostasis Therapeutics announces intention to submit IND applications for PTI 801 and PTI 808 to US FDA in December 2016
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