Drug Profile


Alternative Names: CCX 168

Latest Information Update: 27 Apr 2017

Price : $50

At a glance

  • Originator ChemoCentryx
  • Developer ChemoCentryx; Mario Negri Institute for Pharmacological Research
  • Class Anti-inflammatories; Cyclopentanes; Piperidines; Small molecules
  • Mechanism of Action Complement C5a receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Anti-neutrophil cytoplasmic antibody-associated vasculitis; Haemolytic uraemic syndrome; Glomerulonephritis
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Anti-neutrophil cytoplasmic antibody-associated vasculitis
  • Phase II Haemolytic uraemic syndrome; IgA nephropathy
  • Phase I Autoimmune disorders
  • Clinical Phase Unknown Glomerulonephritis

Most Recent Events

  • 31 Mar 2017 ChemoCentryx has patent protection for avacopan in USA, Europe, Australia, China, Hong Kong, Israel, Taiwan, Mexico and Singapore
  • 31 Mar 2017 ChemoCentryx has patents pending for avacopan in Canada and Brazil
  • 22 Mar 2017 Clinical trials in Glomerulonephritis in USA (PO)
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