Drug Profile


Alternative Names: AMG 157; Anti-TSLP MAb; MEDI-9929

Latest Information Update: 10 Sep 2017

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At a glance

  • Originator Amgen
  • Developer Amgen; AstraZeneca; Bispebjerg Hospital; Lund University; MedImmune; University of Copenhagen; University of Newcastle, Australia
  • Class Antiasthmatics; Monoclonal antibodies
  • Mechanism of Action Thymic stromal lymphopoietin inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Asthma; Atopic dermatitis

Most Recent Events

  • 06 Sep 2017 Efficacy and adverse events data from the phase IIb PATHWAY trial in Asthma released by Amgen and AstraZeneca
  • 01 Mar 2017 Medimmune completes a phase II trial in Asthma in USA, Bulgaria, Czech Republic, Hungary, Israel, Japan, Latvia, Lithuania, Serbia, South Africa, Ukraine and Slovakia (NCT02054130; EudraCT2013-003269-33)
  • 15 Dec 2016 Biomarkers information updated
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