Lefamulin

Drug Profile

Lefamulin

Alternative Names: BC-3781; BC-3781.Ac; Lefamulin-acetate

Latest Information Update: 16 Jun 2017

Price : $50

At a glance

  • Originator Nabriva Therapeutics
  • Class Alkenes; Antibacterials; Cyclopentanes; Diterpenes; Polycyclic compounds; Small molecules; Thioglycolates
  • Mechanism of Action Peptidyltransferase modulators; Protein 50S ribosomal subunit modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase III Community-acquired pneumonia
  • Phase II Skin and soft tissue infections
  • Preclinical Bacterial infections; Bone and joint infections; Nosocomial pneumonia; Osteomyelitis; Sexually transmitted infections

Most Recent Events

  • 01 May 2017 Nabriva completes a phase III trial in Community-acquired pneumonia in Argentina, Brazil, Russia, South Africa, Thailand, USA, Bosnia and Herzegovina, Latvia, Bulgaria, Hungary, Georgia and Netherlands, Peru, Philippines, Poland, Romania, Serbia and Ukraine (IV) (PO) (NCT02559310)
  • 11 Apr 2017 Nabriva Therapeutics completes enrolment in its phase III LEAP 1 trial for Community-acquired pneumonia
  • 24 Mar 2017 Preclinical trials in Bacterial infections in Austria (IV)
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