Atu 027

Drug Profile

Atu 027

Alternative Names: Atu027

Latest Information Update: 13 Apr 2017

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At a glance

  • Originator Atugen AG
  • Developer Silence Therapeutics; Silence Therapeutics AG
  • Class Antineoplastics; Small interfering RNA
  • Mechanism of Action Protein kinase N3 inhibitors; RNA interference
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase II Pancreatic cancer
  • Phase I Solid tumours
  • Preclinical Head and neck cancer

Most Recent Events

  • 13 Apr 2017 Atu 027 is available for licensing as of 28 Mar 2017.
  • 05 Jan 2016 Silence Therapeutics completes a phase I/II trial in Pancreatic cancer (Combination therapy, Late-stage disease, Metastatic disease) in Germany (EudraCT2012-004429-26)
  • 10 Jan 2015 Silence Therapeutics withdraws a phase Ib trial in Head and neck cancer in the UK (EudraCT2013-004701-83)
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