Alirocumab

Drug Profile

Alirocumab

Alternative Names: ALI; Anti-PCSK9 monoclonal antibody; Anti-proprotein convertase subtilisin kexin type 9 monoclonal antibody; Praluent; REGN-727; SAR-236553

Latest Information Update: 08 Aug 2017

$50 / €47 *
* $ price applies to USA, Canada and Latin America. € price applies to the rest of the world. Final gross prices may vary according to local VAT.

At a glance

  • Originator Regeneron Pharmaceuticals; sanofi-aventis
  • Developer Regeneron Pharmaceuticals; Sanofi; University Hospital Inselspital
  • Class Antihyperlipidaemics; Monoclonal antibodies
  • Mechanism of Action PCSK9 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Hyperlipoproteinaemia type IIa
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Hypercholesterolaemia; Hyperlipoproteinaemia type IIa
  • Phase III Coronary artery disease

Most Recent Events

  • 15 Jun 2017 Alirocumab receives Orphan Drug status for Hyperlipoproteinaemia type IIa in USA
  • 11 Jun 2017 Efficacy and adverse events data from the phase-III ODYSSEY DM - Insulin trial for Hypercholesterolaemia presented at the 77th Scientific Sessions of the American Diabetes Association (ADA-2017)
  • 19 May 2017 Regeneron Pharmaceuticals plans a phase III trial for Hypercholesterolaemia (In children, In adolescents, In adults) (NCT03156621)
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