Research programme: immunoglobulins - Trillium Therapeutics

Drug Profile

Research programme: immunoglobulins - Trillium Therapeutics

Alternative Names: CD47Fc; TTI-622

Latest Information Update: 10 Feb 2017

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At a glance

  • Originator The Hospital for Sick Children; University Health Network
  • Developer The Hospital for Sick Children; Trillium Therapeutics Inc; University Health Network
  • Class Immunoglobulin Fc fragments; Immunoglobulin fusion proteins; Recombinant fusion proteins
  • Mechanism of Action CD47 antigen inhibitors; SIRPA protein stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Preclinical Cancer
  • Discontinued Transplant rejection

Most Recent Events

  • 03 Feb 2017 Preclinical trials in Cancer (Combination therapy) in Canada (Parenteral)
  • 03 Feb 2017 Trillium announces intention to file an IND application for TTI 622 in the second half of 2017
  • 03 Feb 2017 Trillium Therapeutics plans a clinical trial for TTI 622 for the treatment of Cancer in 2018
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