Copanlisib

Drug Profile

Copanlisib

Alternative Names: BAY-806946; BAY84-1236; Copanlisib hydrochloride

Latest Information Update: 20 May 2017

Price : $50

At a glance

  • Originator Bayer Schering Pharma
  • Developer All Ireland Cooperative Oncology Research Group; Bayer HealthCare Pharmaceuticals; H. Lee Moffitt Cancer Center and Research Institute; National Cancer Institute (USA)
  • Class 3-ring heterocyclic compounds; Amides; Antineoplastics; Imidazoles; Morpholines; Pyrimidines; Quinazolines; Small molecules
  • Mechanism of Action 1 Phosphatidylinositol 3 kinase inhibitors; Phosphatidylinositol 3 kinase alpha inhibitors; Phosphatidylinositol 3 kinase beta inhibitors; Phosphatidylinositol 3 kinase delta inhibitors; Phosphatidylinositol 3 kinase delta modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Follicular lymphoma; MALT lymphoma
  • New Molecular Entity Yes

Highest Development Phases

  • Preregistration Follicular lymphoma
  • Phase III MALT lymphoma; Non-Hodgkin's lymphoma
  • Phase II Cholangiocarcinoma; Diffuse large B cell lymphoma; Endometrial cancer; Mantle-cell lymphoma
  • Phase I/II Breast cancer
  • Phase I Solid tumours

Most Recent Events

  • 05 Jun 2017 Bayer plans a phase I pharmacokinetics trial in Germany (NCT03172884)
  • 17 May 2017 Copanlisib receives priority review status for Follicular lymphoma (Second-line therapy or greater) in USA
  • 05 May 2017 Jonsson Comprehensive Cancer Center plans a phase I/II trial for Breast Cancer (Combination therapy, First line therapy) in USA (NCT03128619)
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