Copanlisib

Drug Profile

Copanlisib

Alternative Names: BAY-806946; BAY84-1236

Latest Information Update: 25 Mar 2017

Price : $50

At a glance

  • Originator Bayer Schering Pharma
  • Developer All Ireland Cooperative Oncology Research Group; Bayer HealthCare Pharmaceuticals; H. Lee Moffitt Cancer Center and Research Institute; National Cancer Institute (USA)
  • Class 3-ring heterocyclic compounds; Amides; Antineoplastics; Imidazoles; Morpholines; Pyrimidines; Quinazolines; Small molecules
  • Mechanism of Action 1 Phosphatidylinositol 3 kinase inhibitors; Phosphatidylinositol 3 kinase alpha inhibitors; Phosphatidylinositol 3 kinase beta inhibitors; Phosphatidylinositol 3 kinase delta inhibitors; Phosphatidylinositol 3 kinase delta modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Follicular lymphoma
  • On Fast track

    Fast track status is assigned by the US FDA so therapies with the potential to address unmet needs can move faster through development.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Non-Hodgkin's lymphoma
  • Phase II Cholangiocarcinoma; Diffuse large B cell lymphoma; Endometrial cancer; Mantle-cell lymphoma
  • Phase I/II Breast cancer
  • Phase I Solid tumours

Most Recent Events

  • 16 Feb 2017 Chonnam National University Hospital and Bayer plan a phase I/II trial for Peripheral T-cell or NK/T-cell lymphoma in South Korea (NCT03052933)
  • 17 Jan 2017 Bayer terminates phase IIa trial in Mantle cell lymphoma (Second line therapy or greater) in USA (NCT02455297)
  • 01 Sep 2016 Bayer completes a phase I pharmacodynamics trial for Non-Hodgkin's lymphoma & Solid tumours (including diabetic patients) in France, United Kingdom and Belgium (NCT02155582)
Restricted Access

Oops, it looks like you don’t have a valid subscription to this content. To gain full access to the content and functionality of the AdisInsight database try one of the following.

  • with a username/password associated to an account with a valid subscription
  • Contact your organization’s admin about adding this content to your AdisInsight subscription
  • Request a trial

If you are a subscriber to this content then contact us at AsktheExpert.AdisInsight@springer.com so we can help.

Back to top