JVS 100

Drug Profile

JVS 100

Alternative Names: ACRX-100; JVS-100; SRX-100

Latest Information Update: 09 Feb 2016

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At a glance

  • Originator Cleveland Clinic
  • Developer Juventas Therapeutics; SironRX Therapeutics
  • Class Gene therapies; Heart failure therapies
  • Mechanism of Action Angiogenesis inducing agents; Apoptosis inhibitors; CXCR4 receptor agonists; Gene transference; Leukocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Phase II Heart failure; Peripheral arterial disorders; Peripheral ischaemia
  • Phase I Scars
  • Preclinical Angina pectoris; Myocardial infarction

Most Recent Events

  • 04 Feb 2016 JVS 100 receives Fast Track designation for treatment of Ulcers in peripheral arterial disorders [IM,Injection] in USA
  • 01 Nov 2015 Phase-II clinical trials in Peripheral arterial disorders in USA (IM)
  • 04 Sep 2015 Juventas plans a phase II STOP-PAD trial for Peripheral arterial disorders in USA (NCT02544204)
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