Drug Profile


Alternative Names: Anatabine citrate; Controlled release; RCP-006

Latest Information Update: 04 Nov 2017

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At a glance

  • Originator Star Scientific
  • Developer Rock Creek Pharmaceuticals Inc; Roskamp Institute; Zenith Technology Corporation
  • Class Alkaloids; Small molecules
  • Mechanism of Action Amyloid beta-protein inhibitors; Cholinergic receptor agonists; Glycogen synthase kinase 3 beta inhibitors; NF-kappa B inhibitors; STAT3 transcription factor inhibitors; STAT3 transcription factor modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Alzheimer's disease
  • Phase I Inflammation; Neurological disorders
  • Preclinical Brain injuries; Cognition disorders; Osteoarthritis; Psoriasis; Smoking withdrawal; Thyroiditis
  • No development reported Multiple sclerosis; Ulcerative colitis

Most Recent Events

  • 04 Nov 2017 No recent reports of development identified for preclinical development in Multiple-sclerosis in USA (PO)
  • 04 Nov 2017 No recent reports of development identified for preclinical development in Ulcerative-colitis in USA (PO)
  • 16 May 2016 Rock Creek Pharmaceuticals plans a phase IIa/II trial in Psoriasis (Topical)
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