Research programme: phosphatidylinositol 3-kinase delta inhibitors - Merck & Co

Drug Profile

Research programme: phosphatidylinositol 3-kinase delta inhibitors - Merck & Co

Alternative Names: PI3K-δ inhibitors; XL-499

Latest Information Update: 20 Oct 2015

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At a glance

  • Originator Exelixis
  • Developer Merck & Co
  • Class Small molecules
  • Mechanism of Action Phosphatidylinositol 3 kinase delta inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Preclinical Cancer; Inflammation

Most Recent Events

  • 20 Oct 2015 Preclinical development is ongoing for Inflammation and Cancer in USA
  • 21 Dec 2011 Exelixis grants Merck & Co an exclusive worldwide license to its phophatidylinositol 3-kinase delta inhibitors research and development programme
  • 21 Dec 2011 Preclinical trials in Cancer in USA (unspecified route)
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