Aminopterin - Syntrix Biosystems

Drug Profile

Aminopterin - Syntrix Biosystems

Alternative Names: Aminotrexate; LD-aminopterin; Rac-aminopterin

Latest Information Update: 05 Feb 2016

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At a glance

  • Originator University of Medicine & Dentistry of New Jersey
  • Developer Syntrix Biosystems
  • Class Benzamides; Glutamates; Pterins; Small molecules
  • Mechanism of Action Tetrahydrofolate dehydrogenase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Phase II Psoriasis
  • No development reported Acute lymphoblastic leukaemia; Rheumatoid arthritis

Most Recent Events

  • 03 Aug 2015 Phase-II development is ongoing for Psoriasis and Rheumatoid arthritis
  • 03 Aug 2015 No recent reports on development identified - Phase-II for Acute lymphoblastic leukaemia (In children, In adults) in USA (PO)
  • 28 Feb 2013 Phase-II clinical trials in Rheumatoid arthritis in Ukraine (PO) (NCT01724931)
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