Ciclosporin - Sigmoid Pharma

Drug Profile

Ciclosporin - Sigmoid Pharma

Alternative Names: AlloCol; Cyclosporin - Sigmoid Pharma; Cyclosporine - Sigmoid Pharma; Cyclosporine A - Sigmoid Pharma; CyCol; CyCron; CyLow; Oral cyclosporine - Sigmoid Pharma

Latest Information Update: 11 Apr 2017

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At a glance

  • Originator Sigmoid Pharma
  • Class Antineoplastics; Antipsoriatics; Antirheumatics; Ciclosporins; Eye disorder therapies; Neuroprotectants
  • Mechanism of Action Calcineurin inhibitors; Free radical inhibitors; Immunosuppressants; Mitochondrial permeability transition pore inhibitors; P-glycoprotein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Graft-versus-host disease
  • New Molecular Entity No
  • Available For Licensing Yes - Graft-versus-host disease; Transplant rejection; Ulcerative colitis

Highest Development Phases

  • Phase II Ulcerative colitis
  • Phase I Crohn's disease; Graft-versus-host disease; Psoriasis; Transplant rejection

Most Recent Events

  • 04 Apr 2017 Cyclosporine licensed to Dr. Falk Pharma in Europe for the treatment of Ulcerative colitis, Graft versus host disease and other Gastrointestinal disorders
  • 29 Sep 2014 Cyclosporine licensed to Pendopharm in Canada
  • 08 Sep 2014 Sigmoid Pharma completes enrolment in a phase I trial in Healthy volunteers in United Kingdom (NCT02130414)
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