Drug Profile


Alternative Names: TP-434

Latest Information Update: 23 Jan 2017

Price : $50

At a glance

  • Originator Tetraphase Pharmaceuticals
  • Class Acetamides; Antibacterials; Pyrrolidines; Small molecules; Tetracyclines
  • Mechanism of Action Protein 30S ribosomal subunit inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • On Fast track

    Fast track status is assigned by the US FDA so therapies with the potential to address unmet needs can move faster through development.

    Intra-abdominal infections; Urinary tract infections
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Intra-abdominal infections; Urinary tract infections
  • Phase I Respiratory tract infections

Most Recent Events

  • 15 Dec 2016 Phase-III clinical trials in Urinary tract infections in Austria (IV) (EudraCT2016-002207-26)
  • 15 Dec 2016 Tetraphase Pharmaceuticals initiates enrolment in the IGNITE3 phase III trial in Urinary tract infections in Latvia (IV) (EudraCT2016-002207-26)
  • 17 Nov 2016 Tetraphase Pharmaceuticals announces intention to submit NDA to US FDA for complicated Intra-abdominal infections
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