Oprozomib

Drug Profile

Oprozomib

Alternative Names: ONO-7058; ONX-012; ONX-0912; OPZ; PR-047

Latest Information Update: 22 Feb 2017

Price : $50

At a glance

  • Originator Onyx Pharmaceuticals
  • Class Amides; Antineoplastics; Epoxy compounds; Oligopeptides; Small molecules; Thiazoles
  • Mechanism of Action Apoptosis stimulants; Proteasome inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Multiple myeloma; Waldenstrom's macroglobulinaemia
  • New Molecular Entity Yes
  • Available For Licensing Yes - Multiple myeloma

Highest Development Phases

  • Phase I/II Haematological malignancies; Multiple myeloma
  • Phase I Solid tumours

Most Recent Events

  • 01 Jan 2017 Amgen initiates enrolment in the INTREPID-1 trial for Multiple myeloma (Combination therapy, Second-line therapy or greater) in USA (NCT02939183)
  • 03 Dec 2016 Final adverse events and efficacy data from a phase Ib/II trial in Haematological malignancies presented at the 58th Annual Meeting and Exposition of the American Society of Haematology (ASH-2016)
  • 18 Oct 2016 Amgen plans the phase Ib INTREPID-1 trial for Multiple myeloma (Combination therapy, Second-line therapy or greater) in USA (unspecified route) (NCT029391830)
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