Netupitant/palonosetron

Drug Profile

Netupitant/palonosetron

Alternative Names: Akynzeo; NEPA; NEPA - Helsinn; Netupitant-palonosetron fixed dose combination (NEPA); Palonosetron/netupitant

Latest Information Update: 12 Oct 2017

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At a glance

  • Originator Helsinn
  • Developer Helsinn; Taiho Pharmaceutical; Vifor Pharma
  • Class Antiemetics; Isoquinolines; Pyridines; Quinuclidines; Small molecules
  • Mechanism of Action G protein-coupled receptor modulators; Neurokinin 1 antagonists; Serotonin 3 receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Marketed Chemotherapy-induced nausea and vomiting

Most Recent Events

  • 12 Sep 2017 Clinical trials in Chemotherapy induced nausea and vomiting (Prevention, In Chinese volunteers) (IV) before September 2017
  • 12 Sep 2017 Pharmacokinetics data from a clinical trial and adverse event data from a phase III trial in Chemotherapy induced nausea and vomiting presented at the 42nd European Society for Medical Oncology Congress (ESMO-2017)
  • 31 Jul 2017 Chemical structure information added
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