Drug Profile


Alternative Names: LY2784544

Latest Information Update: 10 Sep 2017

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At a glance

  • Originator Eli Lilly
  • Class 2 ring heterocyclic compounds; Antineoplastics; Small molecules
  • Mechanism of Action Janus kinase-2 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Myeloproliferative disorders
  • Phase I Myelofibrosis
  • Preclinical Solid tumours

Most Recent Events

  • 24 Feb 2017 Eli Lilly completes a phase I trial for Myelofibrosis in USA (NCT01520220)
  • 08 Sep 2015 Gandotinib is still in phase II trials for Myeloproliferative disorders in the USA, Austria, Australia, Canada, France, Germany, Italy, Spain and Sweden
  • 13 Jul 2012 Phase-II clinical trials in Myeloproliferative disorders in Spain (PO)
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